What is POTS?

POTS is a form of dysautonomia — a dysfunction of the autonomic nervous system. This department of the nervous system regulates features we don’t consciously management, corresponding to coronary heart rate, blood pressure, sweating and body temperature. The key traits of POTS are the specific signs and the exaggerated improve in coronary heart rate when standing.

What does POTS stand for?

Postural: related to the position of your body

Orthostatic: related to standing upright

Tachycardia: increased heart rate

Syndrome: a group of signs

Why does coronary heart rate enhance excessively with POTS?

In most patients with POTS, the construction of the guts itself is normal. POTS symptoms arise from a mixture of the following:

Lower amount of blood in the circulation

Excessive pooling of blood below the level of the heart when upright

Elevated levels of sure hormones akin to epinephrine (also known as adrenaline since it is launched by the adrenal glands) and norepinephrine (mainly launched by nerves).

Once we stand, gravity pulls more blood into the decrease half of the body. In a healthy individual, to ensure that a adequate quantity of blood reaches the brain, the body prompts several nervous system responses. One such response is releasing hormones that help tighten blood vessels and cause a modest increase in heart rate. This leads to higher blood flow to the center and brain. As soon as the brain is receiving enough blood and oxygen, these nervous system responses settle back to normal.

In people with POTS, for unclear reasons which will differ from person to person, the blood vessels don’t respond efficiently to the signal to tighten. Because of this, the longer you are upright, the more blood swimming pools in the lower half of your body. This leads to not enough blood returning to the brain, which can be felt as lightheadedness (faintness), brain fog and fatigue. As the nervous system continues to launch epinephrine and norepinephrine to tighten the blood vessels, the heart rate will increase further. This may cause shakiness, forceful or skipped heartbeats, and chest pain.

Some people with POTS can develop hypotension (a drop in blood pressure) with prolonged standing (more than three minutes upright). Others can develop an increase in blood pressure (hypertension) when they stand.

Types and Causes of POTS

The causes of POTS differ from person to person. Researchers don’t entirely understand the origins of this disorder. The classification of POTS is the subject of discussion, however most writerities acknowledge totally different characteristics in POTS, which occur in some patients more than others. Importantly, these traits are not mutually unique; particular person with POTS could experience more than of those at the identical time:

Neuropathic POTS is a time period used to describe POTS associated with damage to the small fiber nerves (small-fiber neuropathy). These nerves regulate the constriction of the blood vessels within the limbs and abdomen.

Hyperadrenergic POTS is a term used to describe POTS associated with elevated levels of the stress hormone norepinephrine.

Hypovolemic POTS is a term used to describe POTS related with abnormally low levels of blood (hypovolemia).

Secondary POTS implies that POTS is associated with another condition known to doubtlessly cause autonomic neuropathy, equivalent to diabetes, Lyme illness, or autoimmune problems such as lupus or Sjögren’s syndrome.

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